Douglas
Hoffman, M.D., Ph.D.
Symptoms:
Many allergy symptoms are well-known and
easily recognized: "runny" nose, sneezing, itching
of the eyes/nose/throat, and nasal congestion are as common as they are
obvious. However, nasal allergy can lead to many
other problems which are not so obvious. These include ear
pain, ear pressure, tinnitus ("head noise"),
hearing loss, cough, sore throat, chronic fatigue,
hoarseness, decreased sense of smell and taste, and globus
sensation (that "something in the back of my throat"
feeling).
Testing:
There are two types of allergy tests: skin
tests and blood tests. Skin tests are more accurate but are,
of course, more irritating. If you are going to be
desensitized to a particular allergen (an allergen is
anything you might be allergic to; examples are ragweed
pollen or cat dander), testing is a necessary prerequisite.
Testing is also very helpful for devising
avoidance strategies. Avoidance (see below) is difficult if
you dont know what to avoid.
Avoidance:
Avoidance is (arguably) the most effective
treatment strategy for dealing with nasal allergies. There
are two problems with avoidance. First, avoidance is only
effective if you have full knowledge of your allergies.
Testing is helpful in this regard, but allergy tests
arent perfect. Second, avoidance is only effective if
you are willing to practice avoidance. A common
example is the cat owner who will not give up her cats (many
pet owners are not even willing to bar their pets from the
bedroom). Avoidance may also be impractical: if you live in
the Pacific Northwest and are allergic to redwood pollen, the
only way to practice avoidance is to leave the area. Some
folks are willing and able to do this, but some folks are
not. Even if you cannot leave the area, however, you can
still minimize your exposure to local allergens.
Certain avoidance strategies are useful to
adopt even in the absence of testing:
*Frequent laundering of bedding.
*Frequent vacuuming of the bedroom
(including underneath the bed), and all carpeted floors.
Ideally, have someone else do the vacuuming! If you
are in a position to avoid using carpets (in favor of wood
floors, tile, etc.) you should do so.
*Keep your bedroom windows closed at
night.
*Use a HEPA filter in your bedroom
throughout the night. HEPA filters clean the air of pollen,
dust, and other particulate matter. The HEPA filter must be
elevated off the ground (otherwise, it will tend to blow dust
into the air, and this is counterproductive!) HEPA filters
cost about $100 to $120. When you buy the HEPA filter, make
sure that replacement filters are also available
(theres a charcoal prefilter as well as the HEPA filter
itself). If you find the HEPA filter to be helpful, you
should consider purchasing replacement filters early, since
models seem to change on a semiannual basis. In other words,
you may not be able to find replacement filters if you shop
for them in 6 months. That's planned obsolescence for you.
Drugs:
Before discussing drugs to treat
allergy, lets talk about other drugs. Tobacco,
marijuana and other inhaled drugs (such as cocaine or crack)
are injurious to the tissues lining the nose (mucosa).
Obviously, these drugs (and other inhaled irritants, such as
cleaning fluids or chemical fumes) should be avoided as much
as possible.
Alcohol is very dehydrating. Poor
hydration leads to thickening of nasal mucus. We all produce
about 4 cups of mucus per day, but we usually dont
notice the mucus; thats because it is usually quite
thin. THICK mucus is OBNOXIOUS mucus.
What about drugs to treat allergy? Most
over the counter drugs are "combination" drugs.
These should be avoided, since you may not need all
components of the combination. In general, decongestants
(sprays such as Afrin or Neosynephrine, or pills containing
pseudoephedrine such as Sudafed) should be used only
to treat acute congestion (due to a cold or a brief bout of
allergies). Long-term use of decongestants often thickens
nasal mucus; long-term use of sprays (longer than 3 or 4
days) leads to dependency. In other words, you could find
yourself using the spray with increasing frequency, and the
spray could worsen your problems with congestion.
One last warning about decongestants: these drugs are
hazardous for patients with particular health conditions
such as high blood pressure. If you have any doubts, ask
your doctor whether that particular drug is safe for you.
Antihistamines (examples include Benadryl,
Chlortrimeton, Allegra, Claritin and Zyrtec) can be very
effective for allergy treatment. Sedation is the most
frequent side effect, even for the so-called
"non-sedating" antihistamines (Allegra, Claritin,
Zyrtec). In recent years, a spray antihistamine (Astelin/azelastine) has
proven quite promising, as it provides the benefits of antihistamines
without the side effects.
Nasal steroid sprays (such as Flonase, Rhinocort, Nasacort,
Nasarel, and Nasonex) blunt
the allergic response and reduce inflammation. They should be
used with caution by patients with eye problems (especially
glaucoma or cataracts). If you have any eye problems, you
should discuss the use of nasal steroid sprays with your eye
doctor. Nasal steroid sprays can, on occasion, cause
excessive nasal dryness and nose bleeds.
Cromalyn sodium spray (Nasalcrom) is, in
my opinion, an excellent over the counter medication for allergy sufferers.
It must be used regularly and, if your allergy problems are severe,
frequently (see package instructions). Nasalcrom has
minimal side effects, and adverse interactions with other medications are
rare.
Desensitization:
Desensitization -- also known as immunotherapy,
but more commonly referred to as "allergy shots" --
has been demonstrated in many well-executed, carefully
controlled clinical studies to be a safe and effective
treatment for nasal allergies. It is particularly useful for
patients with severe allergies who are unable to avoid their
allergens.
Desensitization may take many months (a 12
to 18 month course of therapy is not unusual) and is not
always effective. If the patient responds poorly to
desensitization, there are three common possible
explanations. First, testing may not have revealed the full
range of allergens to which you are sensitive. To take a very
obvious example, lets say you own 6 cats, are allergic
to cats, and yet you have not been tested for an allergy to
cat dander. If you werent tested for it, it is very
unlikely that your course of desensitization covered this
particular allergy.
A second reason for failure is the
development of new allergies during the course of
therapy. You can develop new allergies throughout life.
Finally, your problems may not be due to
allergy at all. Some nasal complaints are due to chronic
sinusitis, which may be thought of as chronic inflammation
(often with bacterial or fungal infection) of the tissues
lining the sinuses. While many patients with chronic
sinusitis improve with desensitization, many do not;
presumably, the individuals who do not improve have little or
no underlying problems with allergies.
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